… in the genetics of the LPA gene, risk categories of elevated … Black, 1,047 White, and 603
Hispanic individuals), the distribution of the major apo(a) isoform reflects the global population …

… the characteristic apolipoprotein(a)(apo(a)). Lp(a) occurs as a quantitative genetic trait with
… The major gene controlling the quantitative Lp(a) trait is LPA which codes for apo(a). Two …

… of the genetic size polymorphism of apo(a)which … Africa and from Gabon demonstrated that
the LPA locus is the major locus determining Lp(a) levels also in autochthonous populations …

… Therefore, unless homozygous for two LPA genes of identical KIV-2 repeat number, most
people have two different isoforms of apo(a). A person with two large isoforms may have low …

… Lp(a) concentrations are particularly dependent on Apo A … associated with smaller Apo A
isoforms and higher Lp(a) … risks are not linked to genetic variation in LPA at SNPs rs6415084, …

… descent, but not resident in Africa, and thus genes chosen may not be appropriate for
indigenous African populations. Furthermore, only eight genes were included in the study and …

… in the African cohort for both timepoints, apolipoprotein(a) (APOA) and Apolipoprotein L1
(… African genetics and way of life on the proteomic signature. Finally, the parent clinical trial …

… Insight into the genetics of Lp(a) is progressing … Africa and from Gabon demonstrated that
the LPA locus is the major locus determining Lp(a) levels also in autochthonous populations …

… with Lp(a) and inflammation we gained relevant information on genetic determinants of Lp(a)
and … B100 (apoB100), and the other part is apolipoprotein a (apo(a)) covalently bound by a …

… the point that due to the great genetic heterogeneity of LPA, it will be hardly possible to have
… (a) is complexed with LDL, and there is an appreciable amount of free apo(a) and apo(a) …